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Lego principle

(principle that life is associated with a skew in molecule abundances)

The Lego principle is an informal name for the idea that life is made up of a relatively small set of molecules that life tends to assemble, so the presence of life will skew the molecule abundances away from the distributions seen without life. Thus, while a biosignature could be the presence of some substance that doesn't occur abiotically, it could also be a distribution that cannot be explained through abiotic processes.

Earth life consists of several amino acids, nucleotides, sugars, and lipids, and this commonality allows lifeforms to interact.